Targeting the EMT transcription factor Snail overcomes resistance to osimertinib in EGFR‐mutant non‐small cell lung cancer

BACKGROUND: The resistance mechanism of the third generation of epidermal growth factor (EGFR) tyrosine kinase inhibitor (TKI) osimertinib is complex. Epithelial mesenchymal transition (EMT) is a common mechanism of EGFR‐TKI acquired resistance. Snail is an important transcription factor related to...

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Detalles Bibliográficos
Autores principales: Qin, Qiong, Li, Xiaoqing, Liang, Xingmei, Zeng, Lili, Wang, Jing, Sun, Linlin, Zhong, Diansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169301/
https://www.ncbi.nlm.nih.gov/pubmed/33943009
http://dx.doi.org/10.1111/1759-7714.13906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169301/
https://www.ncbi.nlm.nih.gov/pubmed/33943009
http://dx.doi.org/10.1111/1759-7714.13906

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