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Efficiency comparison of B6(Cg)-Tyr(c−2j) /J and C57BL/6NTac embryos as hosts for the generation of knockout mice

Careful selection of the host embryo is critical to the efficient production of knockout (KO) mice when injecting mouse embryonic stem (mES) cells into blastocysts. B6(Cg)-Tyr(c−2j)/J (B6 albino) and C57BL/6NTac (B6NTac) strains of mice are widely used to produce host blastocysts for such procedures...

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Detalles Bibliográficos
Autores principales: Ma, Yu’e, He, Lei, Xiang, Lijie, Zhang, Jie, Wang, Jing, Zhu, Wenjing, Cao, Wenni, Zhu, Yichen, Gao, Man, Zhou, Fei, Liu, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169498/
https://www.ncbi.nlm.nih.gov/pubmed/33844149
http://dx.doi.org/10.1007/s11248-021-00248-9