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Efficiency comparison of B6(Cg)-Tyr(c−2j) /J and C57BL/6NTac embryos as hosts for the generation of knockout mice
Careful selection of the host embryo is critical to the efficient production of knockout (KO) mice when injecting mouse embryonic stem (mES) cells into blastocysts. B6(Cg)-Tyr(c−2j)/J (B6 albino) and C57BL/6NTac (B6NTac) strains of mice are widely used to produce host blastocysts for such procedures...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169498/ https://www.ncbi.nlm.nih.gov/pubmed/33844149 http://dx.doi.org/10.1007/s11248-021-00248-9 |