Cargando…

Flavin-dependent halogenases catalyze enantioselective olefin halocyclization

Halocyclization of alkenes is a powerful bond-forming tool in synthetic organic chemistry and a key step in natural product biosynthesis, but catalyzing halocyclization with high enantioselectivity remains a challenging task. Identifying suitable enzymes that catalyze enantioselective halocyclizatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Mondal, Dibyendu, Fisher, Brian F., Jiang, Yuhua, Lewis, Jared C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169660/
https://www.ncbi.nlm.nih.gov/pubmed/34075034
http://dx.doi.org/10.1038/s41467-021-23503-3