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Flavin-dependent halogenases catalyze enantioselective olefin halocyclization

Halocyclization of alkenes is a powerful bond-forming tool in synthetic organic chemistry and a key step in natural product biosynthesis, but catalyzing halocyclization with high enantioselectivity remains a challenging task. Identifying suitable enzymes that catalyze enantioselective halocyclizatio...

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Detalles Bibliográficos
Autores principales:	Mondal, Dibyendu, Fisher, Brian F., Jiang, Yuhua, Lewis, Jared C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169660/ https://www.ncbi.nlm.nih.gov/pubmed/34075034 http://dx.doi.org/10.1038/s41467-021-23503-3

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