Discovery of a cooperative mode of inhibiting RIPK1 kinase

RIPK1, a death domain-containing kinase, has been recognized as an important therapeutic target for inhibiting apoptosis, necroptosis, and inflammation under pathological conditions. RIPK1 kinase inhibitors have been advanced into clinical studies for the treatment of various human diseases. One of...

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Detalles Bibliográficos
Autores principales: Meng, Huyan, Wu, Guowei, Zhao, Xinsuo, Wang, Anhui, Li, Dekang, Tong, Yilun, Jin, Taijie, Cao, Ye, Shan, Bing, Hu, Shichen, Li, Ying, Pan, Lifeng, Tian, Xiaoxu, Wu, Ping, Peng, Chao, Yuan, Junying, Li, Guohui, Tan, Li, Wang, Zhaoyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169668/
https://www.ncbi.nlm.nih.gov/pubmed/34075030
http://dx.doi.org/10.1038/s41421-021-00278-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169668/
https://www.ncbi.nlm.nih.gov/pubmed/34075030
http://dx.doi.org/10.1038/s41421-021-00278-x

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