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Short lifespan of syngeneic transplanted MSC is a consequence of in vivo apoptosis and immune cell recruitment in mice

Mesenchymal stromal cells (MSC) are attractive tools for cell-based therapy, yet the mechanisms underlying their migration and survival post-transplantation are unclear. Accumulating evidence indicates that MSC apoptosis modulates both innate and adaptive immune responses which impact on MSC therape...

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Detalles Bibliográficos
Autores principales: Preda, Mihai Bogdan, Neculachi, Carmen Alexandra, Fenyo, Ioana Madalina, Vacaru, Ana-Maria, Publik, Mihai Alin, Simionescu, Maya, Burlacu, Alexandrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169682/
https://www.ncbi.nlm.nih.gov/pubmed/34075029
http://dx.doi.org/10.1038/s41419-021-03839-w