Combination of consensus and ensemble docking strategies for the discovery of human dihydroorotate dehydrogenase inhibitors

The inconsistencies in the performance of the virtual screening (VS) process, depending on the used software and structural conformation of the protein, is a challenging issue in the drug design and discovery field. Varying performance, especially in terms of early recognition of the potential hit c...

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Detalles Bibliográficos
Autores principales: Chilingaryan, Garri, Abelyan, Narek, Sargsyan, Arsen, Nazaryan, Karen, Serobian, Andre, Zakaryan, Hovakim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169699/
https://www.ncbi.nlm.nih.gov/pubmed/34075175
http://dx.doi.org/10.1038/s41598-021-91069-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169699/
https://www.ncbi.nlm.nih.gov/pubmed/34075175
http://dx.doi.org/10.1038/s41598-021-91069-7

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