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Combination of consensus and ensemble docking strategies for the discovery of human dihydroorotate dehydrogenase inhibitors
The inconsistencies in the performance of the virtual screening (VS) process, depending on the used software and structural conformation of the protein, is a challenging issue in the drug design and discovery field. Varying performance, especially in terms of early recognition of the potential hit c...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169699/ https://www.ncbi.nlm.nih.gov/pubmed/34075175 http://dx.doi.org/10.1038/s41598-021-91069-7 |