Mechanisms of typhoid toxin neutralization by antibodies targeting glycan receptor binding and nuclease subunits

Nearly all clinical isolates of Salmonella Typhi, the cause of typhoid fever, are antibiotic resistant. All S. Typhi isolates secrete an A(2)B(5) exotoxin called typhoid toxin to benefit the pathogen during infection. Here, we demonstrate that antibiotic-resistant S. Typhi secretes typhoid toxin con...

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Detalles Bibliográficos
Autores principales: Ahn, Changhwan, Yang, Yi-An, Neupane, Durga P., Nguyen, Tri, Richards, Angelene F., Sim, Ji Hyun, Mantis, Nicholas J., Song, Jeongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169802/
https://www.ncbi.nlm.nih.gov/pubmed/34113815
http://dx.doi.org/10.1016/j.isci.2021.102454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169802/
https://www.ncbi.nlm.nih.gov/pubmed/34113815
http://dx.doi.org/10.1016/j.isci.2021.102454

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