Dual interleukin-17A/F deficiency protects against acute and chronic response to cigarette smoke exposure in mice

IL-17A and IL-17F are both involved in the pathogenesis of neutrophilic inflammation observed in COPD and severe asthma. To explore this, mice deficient in both Il17a and Il17f and wild type (WT) mice were exposed to cigarette smoke or environmental air for 5 to 28 days and changes in inflammatory c...

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Detalles Bibliográficos
Autores principales: Wada, Hiroo, Nakamura, Masuo, Inoue, Shin-Ichi, Kudo, Akihiko, Hanawa, Tomoko, Iwakura, Yoichiro, Kobayashi, Fumie, Kamma, Hiroshi, Kamiya, Shigeru, Ito, Kazuhiro, Barnes, Peter J., Takizawa, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169846/
https://www.ncbi.nlm.nih.gov/pubmed/34075087
http://dx.doi.org/10.1038/s41598-021-90853-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169846/
https://www.ncbi.nlm.nih.gov/pubmed/34075087
http://dx.doi.org/10.1038/s41598-021-90853-9

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