Abnormal brain cholesterol homeostasis in Alzheimer’s disease—a targeted metabolomic and transcriptomic study

The role of brain cholesterol metabolism in Alzheimer’s disease (AD) remains unclear. Peripheral and brain cholesterol levels are largely independent due to the impermeability of the blood brain barrier (BBB), highlighting the importance of studying the role of brain cholesterol homeostasis in AD. W...

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Detalles Bibliográficos
Autores principales: Varma, Vijay R., Büşra Lüleci, H., Oommen, Anup M., Varma, Sudhir, Blackshear, Chad T., Griswold, Michael E., An, Yang, Roberts, Jackson A., O’Brien, Richard, Pletnikova, Olga, Troncoso, Juan C., Bennett, David A., Çakır, Tunahan, Legido-Quigley, Cristina, Thambisetty, Madhav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169871/
https://www.ncbi.nlm.nih.gov/pubmed/34075056
http://dx.doi.org/10.1038/s41514-021-00064-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169871/
https://www.ncbi.nlm.nih.gov/pubmed/34075056
http://dx.doi.org/10.1038/s41514-021-00064-9

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