ADAM10 and ADAM17 regulate EGFR, c-Met and TNF RI signalling in liver regeneration and fibrosis

ADAM10 and ADAM17 are proteases that affect multiple signalling pathways by releasing molecules from the cell surface. As their substrate specificities partially overlaps, we investigated their concurrent role in liver regeneration and fibrosis, using three liver-specific deficient mouse lines: ADAM...

Descripción completa

Detalles Bibliográficos
Autores principales: Zbodakova, Olga, Chalupsky, Karel, Sarnova, Lenka, Kasparek, Petr, Jirouskova, Marketa, Gregor, Martin, Sedlacek, Radislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169909/
https://www.ncbi.nlm.nih.gov/pubmed/34075077
http://dx.doi.org/10.1038/s41598-021-90716-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169909/
https://www.ncbi.nlm.nih.gov/pubmed/34075077
http://dx.doi.org/10.1038/s41598-021-90716-3

Ejemplares similares