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ADAM10 and ADAM17 regulate EGFR, c-Met and TNF RI signalling in liver regeneration and fibrosis
ADAM10 and ADAM17 are proteases that affect multiple signalling pathways by releasing molecules from the cell surface. As their substrate specificities partially overlaps, we investigated their concurrent role in liver regeneration and fibrosis, using three liver-specific deficient mouse lines: ADAM...
Autores principales: | Zbodakova, Olga, Chalupsky, Karel, Sarnova, Lenka, Kasparek, Petr, Jirouskova, Marketa, Gregor, Martin, Sedlacek, Radislav |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169909/ https://www.ncbi.nlm.nih.gov/pubmed/34075077 http://dx.doi.org/10.1038/s41598-021-90716-3 |
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