Inhibition of MMP2-PEX by a novel ester of dihydroxy cinnamic and linoleic acid from the seagrass Cymodocea serrulata

Matrix metalloproteinases (MMPs) are pivotal for cancer cell migration and metastasis which are generally over-expressed in such cell types. Many drugs targeting MMPs do so by binding to the conserved catalytic domains and thus exhibit poor selectivity due to domain-similarities with other proteases...

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Detalles Bibliográficos
Autores principales: Christina, V. S., Sundaram, R. Lakshmi, Sivamurugan, V., Kumar, D. Thirumal, Mohanapriya, C. D., Shailaja, V. L., Thyagarajan, S. P., Doss, C. George Priya, Gnanambal, K. Mary Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169913/
https://www.ncbi.nlm.nih.gov/pubmed/34075089
http://dx.doi.org/10.1038/s41598-021-90845-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169913/
https://www.ncbi.nlm.nih.gov/pubmed/34075089
http://dx.doi.org/10.1038/s41598-021-90845-9

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