Integrating protein networks and machine learning for disease stratification in the Hereditary Spastic Paraplegias

The Hereditary Spastic Paraplegias are a group of neurodegenerative diseases characterized by spasticity and weakness in the lower body. Owing to the combination of genetic diversity and variable clinical presentation, the Hereditary Spastic Paraplegias are a strong candidate for protein-protein int...

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Detalles Bibliográficos
Autores principales: Vavouraki, Nikoleta, Tomkins, James E., Kara, Eleanna, Houlden, Henry, Hardy, John, Tindall, Marcus J., Lewis, Patrick A., Manzoni, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169945/
https://www.ncbi.nlm.nih.gov/pubmed/34113825
http://dx.doi.org/10.1016/j.isci.2021.102484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169945/
https://www.ncbi.nlm.nih.gov/pubmed/34113825
http://dx.doi.org/10.1016/j.isci.2021.102484

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