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Integrating protein networks and machine learning for disease stratification in the Hereditary Spastic Paraplegias
The Hereditary Spastic Paraplegias are a group of neurodegenerative diseases characterized by spasticity and weakness in the lower body. Owing to the combination of genetic diversity and variable clinical presentation, the Hereditary Spastic Paraplegias are a strong candidate for protein-protein int...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169945/ https://www.ncbi.nlm.nih.gov/pubmed/34113825 http://dx.doi.org/10.1016/j.isci.2021.102484 |