Pro- and anti-apoptotic fate decisions induced by di- and trimeric synthetic cytokine receptors

Synthetic strategies to activate cytokine receptors so far only address standard dimeric cytokine receptor assemblies. The 19 ligands of the tumor necrosis factor superfamily (TNFSF), however, form noncovalent trimers and receptor trimerization is considered to be essential for receptor activation....

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Detalles Bibliográficos
Autores principales: Mossner, Sofie, Floss, Doreen Manuela, Scheller, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169946/
https://www.ncbi.nlm.nih.gov/pubmed/34113818
http://dx.doi.org/10.1016/j.isci.2021.102471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169946/
https://www.ncbi.nlm.nih.gov/pubmed/34113818
http://dx.doi.org/10.1016/j.isci.2021.102471

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