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Pro- and anti-apoptotic fate decisions induced by di- and trimeric synthetic cytokine receptors
Synthetic strategies to activate cytokine receptors so far only address standard dimeric cytokine receptor assemblies. The 19 ligands of the tumor necrosis factor superfamily (TNFSF), however, form noncovalent trimers and receptor trimerization is considered to be essential for receptor activation....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169946/ https://www.ncbi.nlm.nih.gov/pubmed/34113818 http://dx.doi.org/10.1016/j.isci.2021.102471 |