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Targeting Smyd3 by next-generation antisense oligonucleotides suppresses liver tumor growth

The oncogenic function of suppressor of variegation, enhancer of zeste and MYeloid-Nervy-DEAF1-domain family methyltransferase Smyd3 has been implicated in various malignancies, including hepatocellular carcinoma (HCC). Here, we show that targeting Smyd3 by next-generation antisense oligonucleotides...

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Detalles Bibliográficos
Autores principales: Kontaki, Haroula, Koukaki, Marina, Vasilarou, Maria, Giakountis, Antonis, Deligianni, Elena, Luo, Xiaolin, Kim, Youngsoo, Talianidis, Iannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169948/
https://www.ncbi.nlm.nih.gov/pubmed/34113819
http://dx.doi.org/10.1016/j.isci.2021.102473