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Thermal and Acidic Treatments of Gluten Epitopes Affect Their Recognition by HLA-DQ2 in silico

Celiac disease (CD) is a prevalent disorder with autoimmune features. Dietary exposure of wheat gluten (including gliadins and glutenins) to the small intestine activates the gluten-reactive CD4(+) T cells and controls the disease development. While the human leukocyte antigen (HLA) is the single mo...

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Detalles Bibliográficos
Autores principales: Gao, Jihui, Du, Haolan, Zhou, Zekun, Liang, Zhongxin, Liang, Hongrui, Zhang, PeiAo, Wei, Xue, Liu, Shujun, Fu, Linglin, Wang, Yanbo, Che, Huilian, Xue, Wentong, Xin, Fengjiao, Yang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169964/
https://www.ncbi.nlm.nih.gov/pubmed/34095188
http://dx.doi.org/10.3389/fnut.2021.647750