Cargando…
Replication protein A plays multifaceted roles complementary to specialized helicases in processing G-quadruplex DNA
G-quadruplexes (G4s) are non-canonical DNA structures with critical roles in DNA metabolisms. To resolve those structures that can cause replication fork stalling and genomic instability, single-stranded DNA-binding proteins and helicases are required. Here, we characterized the interplay between RP...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169993/ https://www.ncbi.nlm.nih.gov/pubmed/34113828 http://dx.doi.org/10.1016/j.isci.2021.102493 |