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Systemic administration of monovalent follistatin-like 3-Fc-fusion protein increases muscle mass in mice

Targeting the signaling pathway of growth differentiation factor 8 (GDF8), also known as myostatin, has been regarded as a promising strategy to increase muscle mass in the elderly and in patients. Accumulating evidence in animal models and clinical trials has indicated that a rational approach is t...

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Detalles Bibliográficos
Autores principales: Ozawa, Takayuki, Morikawa, Masato, Morishita, Yasuyuki, Ogikubo, Kazuki, Itoh, Fumiko, Koinuma, Daizo, Nygren, Per-Åke, Miyazono, Kohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170004/
https://www.ncbi.nlm.nih.gov/pubmed/34113826
http://dx.doi.org/10.1016/j.isci.2021.102488