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Systemic administration of monovalent follistatin-like 3-Fc-fusion protein increases muscle mass in mice
Targeting the signaling pathway of growth differentiation factor 8 (GDF8), also known as myostatin, has been regarded as a promising strategy to increase muscle mass in the elderly and in patients. Accumulating evidence in animal models and clinical trials has indicated that a rational approach is t...
Autores principales: | Ozawa, Takayuki, Morikawa, Masato, Morishita, Yasuyuki, Ogikubo, Kazuki, Itoh, Fumiko, Koinuma, Daizo, Nygren, Per-Åke, Miyazono, Kohei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170004/ https://www.ncbi.nlm.nih.gov/pubmed/34113826 http://dx.doi.org/10.1016/j.isci.2021.102488 |
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