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Physical exercise is a risk factor for amyotrophic lateral sclerosis: Convergent evidence from Mendelian randomisation, transcriptomics and risk genotypes

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a universally fatal neurodegenerative disease. ALS is determined by gene-environment interactions and improved understanding of these interactions may lead to effective personalised medicine. The role of physical exercise in the development of ALS i...

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Detalles Bibliográficos
Autores principales: Julian, Thomas H, Glascow, Nicholas, Barry, A Dylan Fisher, Moll, Tobias, Harvey, Calum, Klimentidis, Yann C, Newell, Michelle, Zhang, Sai, Snyder, Michael P, Cooper-Knock, Johnathan, Shaw, Pamela J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170114/
https://www.ncbi.nlm.nih.gov/pubmed/34051439
http://dx.doi.org/10.1016/j.ebiom.2021.103397