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The Expression of Chemokines Is Downregulated in a Pre-Clinical Model of TTR V30M Amyloidosis

Inflammation is a hallmark of several neurodegenerative disorders including hereditary amyloidogenic transthyretin amyloidosis (ATTRv). ATTRv is an autosomal dominant neurodegenerative disorder with extracellular deposition of mutant transthyretin (TTR) aggregates and fibrils, particularly in nerves...

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Detalles Bibliográficos
Autores principales: Moreira, João, Costelha, Susete, Saraiva, Margarida, Saraiva, Maria João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170140/
https://www.ncbi.nlm.nih.gov/pubmed/34093538
http://dx.doi.org/10.3389/fimmu.2021.650269