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Downregulation of miR-483-5p inhibits TGF-β1-induced EMT by targeting RhoGDI1 in pulmonary fibrosis

Transforming growth factor-β1 (TGF-β1)-induced epithelial-mesenchymal transition (EMT) serves a significant role in pulmonary fibrosis (PF). Increasing evidence indicates that microRNAs (miRNAs or miRs) contribute to PF pathogenesis via EMT regulation. However, the role of miR-483-5p in PF remains u...

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Detalles Bibliográficos
Autores principales: Huang, Guichuan, Zhang, Jing, Qing, Gang, Liu, Daishun, Wang, Xin, Chen, Yi, Wu, Yongchang, Li, Yishi, Guo, Shuliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170182/
https://www.ncbi.nlm.nih.gov/pubmed/34080651
http://dx.doi.org/10.3892/mmr.2021.12177