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12/15-Lipoxygenase Regulates IL-33-Induced Eosinophilic Airway Inflammation in Mice

Dysregulated fatty acid metabolism is clinically associated with eosinophilic allergic diseases, including severe asthma and chronic rhinosinusitis. This study aimed to demonstrate the role of 12/15-lipoxygenase (12/15-LOX) in interleukin (IL)-33-induced eosinophilic airway inflammation; to this end...

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Detalles Bibliográficos
Autores principales: Miyata, Jun, Yokokura, Yoshiyuki, Moro, Kazuyo, Arai, Hiroyuki, Fukunaga, Koichi, Arita, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170304/
https://www.ncbi.nlm.nih.gov/pubmed/34093589
http://dx.doi.org/10.3389/fimmu.2021.687192