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Highly Multiplexed Phenotyping of Immunoregulatory Proteins in the Tumor Microenvironment by CODEX Tissue Imaging

Immunotherapies are revolutionizing cancer treatment by boosting the natural ability of the immune system. In addition to antibodies against traditional checkpoint molecules or their ligands (i.e., CTLA-4, PD-1, and PD-L1), therapies targeting molecules such as ICOS, IDO-1, LAG-3, OX40, TIM-3, and V...

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Detalles Bibliográficos
Autores principales: Phillips, Darci, Schürch, Christian M., Khodadoust, Michael S., Kim, Youn H., Nolan, Garry P., Jiang, Sizun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170307/
https://www.ncbi.nlm.nih.gov/pubmed/34093591
http://dx.doi.org/10.3389/fimmu.2021.687673