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Dapsone Ameliorates Isoproterenol-Induced Myocardial Infarction via Nrf2/ HO-1; TLR4/ TNF-α Signaling Pathways and the Suppression of Oxidative Stress, Inflammation, and Apoptosis in Rats

Myocardial infarction (MI) is a critical condition that can happen with high doses or rapid termination of beta blockers therapy. The study aimed to evaluate the potential anti-toxic value of DAP against isoproterenol (ISO) - induced MI. Twenty-eight male Wistar rats were used for the study. The rod...

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Detalles Bibliográficos
Autores principales: Abdelzaher, Walaa Yehia, Ahmed, Sabreen Mahmoud, Welson, Nermeen N., Alsharif, Khalaf F., Batiha, Gaber El-Saber, Labib, Dina A. Aly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170324/
https://www.ncbi.nlm.nih.gov/pubmed/34093197
http://dx.doi.org/10.3389/fphar.2021.669679