Inner Nuclear Membrane Asi Ubiquitin Ligase Catalytic Subunits Asi1p and Asi3p, but not Asi2p, confer resistance to aminoglycoside hygromycin B in Saccharomyces cerevisiae

The heterotrimeric Asi ubiquitin ligase (encoded by ASI1, ASI2, and ASI3) mediates protein degradation in the inner nuclear membrane in Saccharomyces cerevisiae. Asi1p and Asi3p possess catalytic domains, while Asi2p functions as an adaptor for a subset of Asi substrates. We hypothesized the Asi com...

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Detalles Bibliográficos
Autores principales: Woodruff, Kelsey A, Richards, Kyle A, Evans, Melissa D, Scott, Abigail R, Voas, Brian M, Irelan, Courtney Broshar, Olesen, James B, Smaldino, Philip J, Rubenstein, Eric M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2021
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170509/
https://www.ncbi.nlm.nih.gov/pubmed/34095778
http://dx.doi.org/10.17912/micropub.biology.000403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170509/
https://www.ncbi.nlm.nih.gov/pubmed/34095778
http://dx.doi.org/10.17912/micropub.biology.000403

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