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Proteome-wide analysis of Coxiella burnetii for conserved T-cell epitopes with presentation across multiple host species

BACKGROUND: Coxiella burnetii is the Gram-negative bacterium responsible for Q fever in humans and coxiellosis in domesticated agricultural animals. Previous vaccination efforts with whole cell inactivated bacteria or surface isolated proteins confer protection but can produce a reactogenic immune r...

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Detalles Bibliográficos
Autores principales: Piel, Lindsay M. W., Durfee, Codie J., White, Stephen N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170629/
https://www.ncbi.nlm.nih.gov/pubmed/34078271
http://dx.doi.org/10.1186/s12859-021-04181-w