Allostery through DNA drives phenotype switching

Allostery is a pervasive principle to regulate protein function. Growing evidence suggests that also DNA is capable of transmitting allosteric signals. Yet, whether and how DNA-mediated allostery plays a regulatory role in gene expression remained unclear. Here, we show that DNA indeed transmits all...

Descripción completa

Detalles Bibliográficos
Autores principales: Rosenblum, Gabriel, Elad, Nadav, Rozenberg, Haim, Wiggers, Felix, Jungwirth, Jakub, Hofmann, Hagen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170675/
https://www.ncbi.nlm.nih.gov/pubmed/34016970
http://dx.doi.org/10.1038/s41467-021-23148-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170675/
https://www.ncbi.nlm.nih.gov/pubmed/34016970
http://dx.doi.org/10.1038/s41467-021-23148-2

Ejemplares similares