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Allostery through DNA drives phenotype switching
Allostery is a pervasive principle to regulate protein function. Growing evidence suggests that also DNA is capable of transmitting allosteric signals. Yet, whether and how DNA-mediated allostery plays a regulatory role in gene expression remained unclear. Here, we show that DNA indeed transmits all...
Autores principales: | Rosenblum, Gabriel, Elad, Nadav, Rozenberg, Haim, Wiggers, Felix, Jungwirth, Jakub, Hofmann, Hagen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170675/ https://www.ncbi.nlm.nih.gov/pubmed/34016970 http://dx.doi.org/10.1038/s41467-021-23148-2 |
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