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Direct effects of mast cell proteases, tryptase and chymase, on bronchial epithelial integrity proteins and anti-viral responses

BACKGROUND: Mast cells (MCs) are known to contribute to both acute and chronic inflammation. Bronchial epithelial cells are the first line of defence against pathogens and a deficient anti-viral response has been suggested to play a role in the pathogenesis of asthma exacerbations. However, effects...

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Detalles Bibliográficos
Autores principales: Ramu, Sangeetha, Akbarshahi, Hamid, Mogren, Sofia, Berlin, Frida, Cerps, Samuel, Menzel, Mandy, Hvidtfeldt, Morten, Porsbjerg, Celeste, Uller, Lena, Andersson, Cecilia K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170739/
https://www.ncbi.nlm.nih.gov/pubmed/34078278
http://dx.doi.org/10.1186/s12865-021-00424-w