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Mural cell dysfunction leads to altered cerebrovascular tau uptake following repetitive head trauma
A pathological characteristic of repetitive traumatic brain injury (TBI) is the deposition of hyperphosphorylated and aggregated tau species in the brain and increased levels of extracellular monomeric tau are believed to play a role in the pathogenesis of neurodegenerative tauopathies. The pathways...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170787/ https://www.ncbi.nlm.nih.gov/pubmed/33383188 http://dx.doi.org/10.1016/j.nbd.2020.105237 |