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Mural cell dysfunction leads to altered cerebrovascular tau uptake following repetitive head trauma

A pathological characteristic of repetitive traumatic brain injury (TBI) is the deposition of hyperphosphorylated and aggregated tau species in the brain and increased levels of extracellular monomeric tau are believed to play a role in the pathogenesis of neurodegenerative tauopathies. The pathways...

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Detalles Bibliográficos
Autores principales: Ojo, Joseph, Eisenbaum, Max, Shackleton, Ben, Lynch, Cillian, Joshi, Utsav, Saltiel, Nicole, Pearson, Andrew, Ringland, Charis, Paris, Daniel, Mouzon, Benoit, Mullan, Michael, Crawford, Fiona, Bachmeier, Corbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170787/
https://www.ncbi.nlm.nih.gov/pubmed/33383188
http://dx.doi.org/10.1016/j.nbd.2020.105237