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Subcellular localization of the mouse PRAMEL1 and PRAMEX1 reveals multifaceted roles in the nucleus and cytoplasm of germ cells during spermatogenesis

BACKGROUND: Preferentially expressed antigen in melanoma (PRAME) is a cancer/testis antigen (CTA) that is predominantly expressed in normal gametogenic tissues and a variety of tumors. Members of the PRAME gene family encode leucine-rich repeat (LRR) proteins that provide a versatile structural fram...

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Detalles Bibliográficos
Autores principales: Liu, Wan-Sheng, Lu, Chen, Mistry, Bhavesh V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170798/
https://www.ncbi.nlm.nih.gov/pubmed/34074333
http://dx.doi.org/10.1186/s13578-021-00612-6