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Apt (Adenine Phosphoribosyltransferase) Mutation in Laboratory-Selected Vancomycin-Intermediate Staphylococcus aureus

Comparative genomic sequencing of laboratory-derived vancomycin-intermediate Staphylococcus aureus (VISA) (MM66-3 and MM66-4) revealed unique mutations in both MM66-3 (in apt and ssaA6), and MM66-4 (in apt and walK), compared to hetero-VISA parent strain MM66. Transcriptional profiling revealed that...

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Detalles Bibliográficos
Autores principales: Lamichhane-Khadka, Reena, Dulal, Santosh, Cuaron, Jesus A., Pfeltz, Richard, Gupta, Sushim Kumar, Wilkinson, Brian J., Gustafson, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170892/
https://www.ncbi.nlm.nih.gov/pubmed/34069103
http://dx.doi.org/10.3390/antibiotics10050583