Effective DNA damage response after acute but not chronic immune challenge: SARS-CoV-2 vaccine versus Systemic Lupus Erythematosus

Whether and how an acute immune challenge may affect DNA Damage Response (DDR) is unknown. By studying vaccinations against Influenza and SARS-CoV-2 (mRNA-based) we found acute increases of type-I interferon-inducible gene expression, oxidative stress and DNA damage accumulation in blood mononuclear...

Descripción completa

Detalles Bibliográficos
Autores principales: Ntouros, Panagiotis A., Vlachogiannis, Nikolaos I., Pappa, Maria, Nezos, Adrianos, Mavragani, Clio P., Tektonidou, Maria G., Souliotis, Vassilis L., Sfikakis, Petros P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171000/
https://www.ncbi.nlm.nih.gov/pubmed/34089859
http://dx.doi.org/10.1016/j.clim.2021.108765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171000/
https://www.ncbi.nlm.nih.gov/pubmed/34089859
http://dx.doi.org/10.1016/j.clim.2021.108765

Ejemplares similares