Cargando…

Effective DNA damage response after acute but not chronic immune challenge: SARS-CoV-2 vaccine versus Systemic Lupus Erythematosus

Whether and how an acute immune challenge may affect DNA Damage Response (DDR) is unknown. By studying vaccinations against Influenza and SARS-CoV-2 (mRNA-based) we found acute increases of type-I interferon-inducible gene expression, oxidative stress and DNA damage accumulation in blood mononuclear...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ntouros, Panagiotis A., Vlachogiannis, Nikolaos I., Pappa, Maria, Nezos, Adrianos, Mavragani, Clio P., Tektonidou, Maria G., Souliotis, Vassilis L., Sfikakis, Petros P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2021
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171000/ https://www.ncbi.nlm.nih.gov/pubmed/34089859 http://dx.doi.org/10.1016/j.clim.2021.108765

Ejemplares similares

Association Between DNA Damage Response, Fibrosis and Type I Interferon Signature in Systemic Sclerosis
por: Vlachogiannis, Nikolaos I., et al.
Publicado: (2020)

DNA Damage Response and Oxidative Stress in Systemic Autoimmunity
por: Souliotis, Vassilis L., et al.
Publicado: (2019)

Oxidative stress and endogenous DNA damage in blood mononuclear cells may predict anti-SARS-CoV-2 antibody titers after vaccination in older adults
por: Ntouros, Panagiotis A., et al.
Publicado: (2022)

Adenosine-to-inosine RNA editing contributes to type I interferon responses in systemic sclerosis
por: Vlachogiannis, Nikolaos I., et al.
Publicado: (2021)

Osteoprotegerin and MTHFR gene variations in rheumatoid arthritis: association with disease susceptibility and markers of subclinical atherosclerosis
por: Arida, Aikaterini, et al.
Publicado: (2022)

Contribution of Genetic Factors to Sjögren's Syndrome and Sjögren's Syndrome Related Lymphomagenesis
por: Nezos, Adrianos, et al.
Publicado: (2015)

Chronological Age and DNA Damage Accumulation in Blood Mononuclear Cells: A Linear Association in Healthy Humans after 50 Years of Age
por: Vlachogiannis, Nikolaos I., et al.
Publicado: (2023)

Microvasculopathy-Related Hemorrhagic Tissue Deposition of Iron May Contribute to Fibrosis in Systemic Sclerosis: Hypothesis-Generating Insights from the Literature and Preliminary Findings
por: Sfikakis, Petros P., et al.
Publicado: (2022)

Defective DNA repair and chromatin organization in patients with quiescent systemic lupus erythematosus
por: Souliotis, Vassilis L., et al.
Publicado: (2016)

MTHFR gene variants and non-MALT lymphoma development in primary Sjogren’s syndrome
por: Fragkioudaki, Sofia, et al.
Publicado: (2017)

B-cell Activating Factor Polymorphisms in Rheumatoid Arthritis-Associated Atherosclerosis
por: Kintrilis, Nikolaos, et al.
Publicado: (2021)

Milk Fat Globule Epidermal Growth Factor 8 (MFGE8) Gene Variants in Rheumatoid Arthritis and Sjögren’s Syndrome
por: Skarlis, Charalampos, et al.
Publicado: (2022)

The Role of Novel Autoantibodies in the Diagnostic Approach and Prognosis of Patients with Raynaud’s Phenomenon
por: Koulouri, Vasiliki, et al.
Publicado: (2020)

TNFAIP3 F127C Coding Variation in Greek Primary Sjogren's Syndrome Patients
por: Nezos, Adrianos, et al.
Publicado: (2018)

+3179G/A Insulin-Like Growth Factor-1 Receptor Polymorphism: A Novel Susceptibility Contributor in Anti-Ro/SSA Positive Patients with Sjögren’s Syndrome: Potential Clinical and Pathogenetic Implications
por: Skarlis, Charalampos, et al.
Publicado: (2021)

Impaired hand function and performance in activities of daily living in systemic lupus erythematosus, even in patients achieving lupus low disease activity state (LLDAS)
por: Keramiotou, Kyriaki, et al.
Publicado: (2021)

Differentiating central nervous system demyelinating disorders: The role of clinical, laboratory, imaging characteristics and peripheral blood type I interferon activity
por: Karathanasis, Dimitris K., et al.
Publicado: (2022)

Lipid management in systemic lupus erythematosus according to risk classifiers suggested by the European Society of Cardiology and disease-related risk factors reported by the EULAR recommendations
por: Drosos, George C, et al.
Publicado: (2023)

Leukocyte Immunoglobulin-Like Receptor A3 (LILRA3): A Novel Marker for Lymphoma Development among Patients with Young Onset Sjogren’s Syndrome
por: Argyriou, Evangelia, et al.
Publicado: (2021)

The impact of upper limb exercise on function, daily activities and quality of life in systemic lupus erythematosus: a pilot randomised controlled trial
por: Keramiotou, Kyriaki, et al.
Publicado: (2020)

Impact of the COVID-19 pandemic in patients with systemic lupus erythematosus throughout one year
por: Ramirez, Giuseppe A., et al.
Publicado: (2021)

Activation of Type I Interferon Pathway in Systemic Lupus Erythematosus: Association with Distinct Clinical Phenotypes
por: Karageorgas, Theophanis P., et al.
Publicado: (2011)

Increased adenosine-to-inosine RNA editing in rheumatoid arthritis
por: Vlachogiannis, Nikolaos I., et al.
Publicado: (2020)

Phenotypic characterization of patients with activated PI3Kδ syndrome 1 presenting with features of systemic lupus erythematosus
por: Wang, Yanping, et al.
Publicado: (2020)

Systemic lupus erythematosus with antiphospholipid syndrome: Cardiovascular magnetic resonance for evaluation of cardiac hypertrophy
por: Mavrogeni, Sophie I., et al.
Publicado: (2017)

Study of the incidence of osteoporosis in patients with Sjögren’s syndrome (pSS) and investigation of activation of the RANKL /RANK and osteoprotegerin (OPG) system
por: Skarlis, Charalampos, et al.
Publicado: (2018)

Lipoprotein-Associated Phospholipase A2: A Novel Contributor in Sjögren’s Syndrome-Related Lymphoma?
por: Nezos, Adrianos, et al.
Publicado: (2021)

Metabolic syndrome in antiphospholipid syndrome versus rheumatoid arthritis and diabetes mellitus: Association with arterial thrombosis, cardiovascular risk biomarkers, physical activity, and coronary atherosclerotic plaques
por: Bolla, Eleana, et al.
Publicado: (2023)

Disease modification achievement in patients with lupus nephritis in a real-life setting: mission impossible?
por: Panagiotopoulos, Alexandros, et al.
Publicado: (2023)

Extensive fragmentation and re-organization of transcription in Systemic Lupus Erythematosus
por: Ntasis, Vasilis F., et al.
Publicado: (2020)

Anxiety and Extraversion in Lupus-Related Atherosclerosis
por: Giannelou, Maira, et al.
Publicado: (2018)

New Insights Into an Overlooked Entity: Long-Term Outcomes of Membranous Lupus Nephritis From a Single Institution Inception Cohort
por: Kapsia, Eleni, et al.
Publicado: (2022)

Real-Life Outcome of Lupus Nephritis with Current Therapies: Study Protocol of a Multicentre Observational Study
por: Pappa, Maria, et al.
Publicado: (2022)

Inhibition of B lymphocyte-induced maturation protein-1 reduces the production of autoantibody and alleviates symptoms of systemic lupus erythematosus
por: Luo, Jie, et al.
Publicado: (2015)

Long-term outcomes in systemic lupus erythematosus: trends over time and major contributors
por: Arnaud, Laurent, et al.
Publicado: (2020)

Alterations in cortisol and interleukin-6 secretion in patients with COVID-19 suggestive of neuroendocrine-immune adaptations
por: Yavropoulou, Maria P., et al.
Publicado: (2022)

Systemic Lupus Erythematosus and COVID-19
por: Pappa, Maria, et al.
Publicado: (2023)

The role of A-to-I RNA editing in infections by RNA viruses: Possible implications for SARS-CoV-2 infection
por: Vlachogiannis, Nikolaos I., et al.
Publicado: (2021)

Predictors of Early Response, Flares, and Long-Term Adverse Renal Outcomes in Proliferative Lupus Nephritis: A 100-Month Median Follow-Up of an Inception Cohort
por: Kapsia, Eleni, et al.
Publicado: (2022)

OGG1 DNA Repair Gene Polymorphism As a Biomarker of Oxidative and Genotoxic DNA Damage
por: Miglani, Kanika, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7pu2nbqbvhlpabru27vgiu0tij