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Crystallographic fragment screening-based study of a novel FAD-dependent oxidoreductase from Chaetomium thermophilum

The FAD-dependent oxidoreductase from Chaetomium thermophilum (CtFDO) is a novel thermostable glycoprotein from the glucose–methanol–choline (GMC) oxidoreductase superfamily. However, CtFDO shows no activity toward the typical substrates of the family and high-throughput screening with around 1000 c...

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Detalles Bibliográficos
Autores principales: Švecová, Leona, Østergaard, Lars Henrik, Skálová, Tereza, Schnorr, Kirk Matthew, Koval’, Tomáš, Kolenko, Petr, Stránský, Jan, Sedlák, David, Dušková, Jarmila, Trundová, Mária, Hašek, Jindřich, Dohnálek, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171062/
https://www.ncbi.nlm.nih.gov/pubmed/34076590
http://dx.doi.org/10.1107/S2059798321003533