An innovative NRF2 nano-modulator induces lung cancer ferroptosis and elicits an immunostimulatory tumor microenvironment

Simultaneous targeting of both the tumor microenvironment and cancer cells by a single nanomedicine has not been reported to date. Here, we report the dual properties of zero-valent-iron nanoparticle (ZVI-NP) to induce cancer-specific cytotoxicity and anti-cancer immunity. Methods: Cancer-specific c...

Descripción completa

Detalles Bibliográficos
Autores principales: Hsieh, Chih-Hsiung, Hsieh, Hung-Chia, Shih, Fu-Hsuan, Wang, Pei-Wen, Yang, Li-Xing, Shieh, Dar-Bin, Wang, Yi-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171079/
https://www.ncbi.nlm.nih.gov/pubmed/34093872
http://dx.doi.org/10.7150/thno.57803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171079/
https://www.ncbi.nlm.nih.gov/pubmed/34093872
http://dx.doi.org/10.7150/thno.57803

Ejemplares similares