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An innovative NRF2 nano-modulator induces lung cancer ferroptosis and elicits an immunostimulatory tumor microenvironment

Simultaneous targeting of both the tumor microenvironment and cancer cells by a single nanomedicine has not been reported to date. Here, we report the dual properties of zero-valent-iron nanoparticle (ZVI-NP) to induce cancer-specific cytotoxicity and anti-cancer immunity. Methods: Cancer-specific c...

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Detalles Bibliográficos
Autores principales:	Hsieh, Chih-Hsiung, Hsieh, Hung-Chia, Shih, Fu-Hsuan, Wang, Pei-Wen, Yang, Li-Xing, Shieh, Dar-Bin, Wang, Yi-Ching
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171079/ https://www.ncbi.nlm.nih.gov/pubmed/34093872 http://dx.doi.org/10.7150/thno.57803

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