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Bi-directional regulation functions of lanthanum-substituted layered double hydroxide nanohybrid scaffolds via activating osteogenesis and inhibiting osteoclastogenesis for osteoporotic bone regeneration

Rationale: Osteoporotic patients suffer symptoms of excessive osteoclastogenesis and impaired osteogenesis, resulting in a great challenge to treat osteoporosis-related bone defects. Based on the positive effect of rare earth elements on bone metabolism and bone regeneration, we try to prove the hyp...

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Detalles Bibliográficos
Autores principales: Chu, Min, Sun, Zhenyu, Fan, Zhanghao, Yu, Degang, Mao, Yuanqing, Guo, Yaping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171081/
https://www.ncbi.nlm.nih.gov/pubmed/34093849
http://dx.doi.org/10.7150/thno.56607