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Tanshinone I, a new EZH2 inhibitor restricts normal and malignant hematopoiesis through upregulation of MMP9 and ABCG2

Rationale: Tanshinone, a type of diterpenes derived from salvia miltiorrhiza, is a particularly promising herbal medicine compound for the treatment of cancers including acute myeloid leukemia (AML). However, the therapeutic function and the underlying mechanism of Tanshinone in AML are not clear, a...

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Detalles Bibliográficos
Autores principales: Huang, Ying, Yu, Shan-He, Zhen, Wen-Xuan, Cheng, Tao, Wang, Dan, Lin, Jie-Bo, Wu, Yu-Han, Wang, Yi-Fan, Chen, Yi, Shu, Li-Ping, Wang, Yi, Sun, Xiao-Jian, Zhou, Yi, Yang, Fan, Hsu, Chih-Hung, Xu, Peng-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171091/
https://www.ncbi.nlm.nih.gov/pubmed/34093860
http://dx.doi.org/10.7150/thno.53170