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Tanshinone I, a new EZH2 inhibitor restricts normal and malignant hematopoiesis through upregulation of MMP9 and ABCG2
Rationale: Tanshinone, a type of diterpenes derived from salvia miltiorrhiza, is a particularly promising herbal medicine compound for the treatment of cancers including acute myeloid leukemia (AML). However, the therapeutic function and the underlying mechanism of Tanshinone in AML are not clear, a...
Autores principales: | Huang, Ying, Yu, Shan-He, Zhen, Wen-Xuan, Cheng, Tao, Wang, Dan, Lin, Jie-Bo, Wu, Yu-Han, Wang, Yi-Fan, Chen, Yi, Shu, Li-Ping, Wang, Yi, Sun, Xiao-Jian, Zhou, Yi, Yang, Fan, Hsu, Chih-Hung, Xu, Peng-Fei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171091/ https://www.ncbi.nlm.nih.gov/pubmed/34093860 http://dx.doi.org/10.7150/thno.53170 |
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