Local administration of liposomal-based Srpx2 gene therapy reverses pulmonary fibrosis by blockading fibroblast-to-myofibroblast transition

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive fatal interstitial lung disease characterized by abnormal transition and proliferation of fibroblasts. The uncontrolled transition of fibroblasts, commonly known as myofibroblasts, are the principal source of the enormous extracellular...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Liu, Juan, Hu, Yinan, Pan, Ting, Xu, Yongjian, Yu, Jun, Xiong, Weining, Zhou, Qing, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171094/
https://www.ncbi.nlm.nih.gov/pubmed/34093874
http://dx.doi.org/10.7150/thno.61085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171094/
https://www.ncbi.nlm.nih.gov/pubmed/34093874
http://dx.doi.org/10.7150/thno.61085

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