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Genomic and transcriptional alterations in first-line chemotherapy exert a potentially unfavorable influence on subsequent immunotherapy in NSCLC

Background: Recent studies in non-small cell lung cancer (NSCLC) patients have demonstrated that first-line immunotherapy is associated with better therapeutic response than second-line treatment. So far, the mechanisms need to be explored. It prompted us to evaluate the association between first-li...

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Detalles Bibliográficos
Autores principales: He, Yayi, Chen, Linsong, Zhao, Lishu, Dang, Shiying, Liu, Guifeng, Sasada, Shinji, Ma, Patrick C., van Zandwijk, Nico, Rosell, Rafael, Popper, Helmut H., Wang, Hao, Jiang, Minlin, Guo, Haoyue, Liu, Xinyi, Chen, Shifu, Zhang, Xiaoni, Xu, Mingyan, Zhu, Bo, Liu, Ming, Zhou, Caicun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171101/
https://www.ncbi.nlm.nih.gov/pubmed/34093873
http://dx.doi.org/10.7150/thno.58039