Enantioselective Michael addition to vinyl phosphonates via hydrogen bond-enhanced halogen bond catalysis

An asymmetric Michael addition of malononitrile to vinyl phosphonates was accomplished by hydrogen bond-enhanced bifunctional halogen bond (XB) catalysis. NMR titration experiments were used to demonstrate that halogen bonding, with the support of hydrogen-bonding, played a key role in the activatio...

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Detalles Bibliográficos
Autores principales: Kaasik, Mikk, Martõnova, Jevgenija, Erkman, Kristin, Metsala, Andrus, Järving, Ivar, Kanger, Tõnis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171314/
https://www.ncbi.nlm.nih.gov/pubmed/34163847
http://dx.doi.org/10.1039/d1sc01029h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171314/
https://www.ncbi.nlm.nih.gov/pubmed/34163847
http://dx.doi.org/10.1039/d1sc01029h

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