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Asymmetric hydroalkylation of alkynes and allenes with imidazolidinone derivatives: α-alkenylation of α-amino acids

This work reports a new method for the synthesis of quaternary α-alkenyl substituted amino acids by the enantio- and diastereoselective addition of imidazolidinone derivatives to alkynes and allenes. Further hydrolysis of the imidazolidinone products under acidic conditions afforded biologically rel...

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Detalles Bibliográficos
Autores principales: Panahi, Farhad, Khosravi, Hormoz, Bauer, Felix, Breit, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171337/
https://www.ncbi.nlm.nih.gov/pubmed/34163828
http://dx.doi.org/10.1039/d1sc00240f