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Rab7-Mediated Endocytosis Establishes Patterning of Wnt Activity through Inactivation of Dkk Antagonism

Endocytosis has been proposed to modulate cell signaling activities. However, the role of endocytosis in embryogenesis, which requires coordination of multiple signaling inputs, has remained less understood. We previously showed that mouse embryos lacking a small guanosine triphosphate (GTP)-binding...

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Detalles Bibliográficos
Autores principales: Kawamura, Nobuyuki, Takaoka, Katsuyoshi, Hamada, Hiroshi, Hadjantonakis, Anna-Katerina, Sun-Wada, Ge-Hong, Wada, Yoh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171381/
https://www.ncbi.nlm.nih.gov/pubmed/32521258
http://dx.doi.org/10.1016/j.celrep.2020.107733